The University of Iowa has achieved a record $705.6 million in external research funding for fiscal year 2025, ending June 30. Of this total, $533.7 million supports research, scholarship, and creative endeavors, with the federal government contributing $300 million (43%) 

Our Stroke Research Spotlight

Supported by the Patient-Centered Outcomes Research Institute, Dr. Santiago Ortega-Gutierrez is leading a major clinical trial that compares imaging strategies to quickly identify and treat severe stroke caused by major artery blockages. The trial will enroll over 2,000 patients across more than 20 stroke centers in the U.S. The aim is to determine which imaging method gets patients to life-saving treatment faster, improving recovery and reducing disability.

This innovative study exemplifies how UI funding is transforming stroke care paradigms, advancing brain science, and contributing to healthier, more resilient communities.

The US FDA has granted 510(k) clearance to Methinks AI’s NCCT Stroke software, a milestone for stroke care and an exciting development in the push for imaging simplification as a gateway to mechanical thrombectomy (EVT).

Using only non-contrast CT (NCCT)—the most accessible imaging modality worldwide Methinks AI’s software can now detect:

• Large vessel occlusions (LVOs)
• Distal occlusions (including M2 segment of the MCA)
• Intracranial hemorrhages (ICHs)

This capability is especially important for hospitals without access to contrast CT or advanced perfusion imaging. By enabling accurate stroke triage using plain CT, Methinks NCCT Stroke offers a scalable tool to support earlier decision-making, faster transfer, and expanded EVT eligibility, even in rural, low-resource, or under-equipped facilities.

“Methinks NCCT can unlock lifesaving decisions at any hospital,” said CEO Pau Rodríguez.
“No patient should be left behind due to imaging limitations.”

In FDA validation studies, the software demonstrated a significant reduction in false negatives compared to other NCCT tools and is uniquely integrated into Microsoft Teams, supporting real-time stroke team collaboration and seamless PACS integration.

This clearance builds on Methinks’ recent partnership with Medtronic, aimed at extending stroke triage solutions across Central and Eastern Europe, Africa, Turkey, and the Middle East.

As the field of stroke care continues to evolve, this announcement strengthens the case for plain CT + AI as a viable front door to EVT, supporting the mission of making advanced stroke care truly global.